5H-dibenz[b,f]azepine-5-carbonitrile
5-Cyano-5H-dibenz[b,f]azepine
CAS: 42787-75-7
Molecular Formula: C15H10N2
5H-dibenz[b,f]azepine-5-carbonitrile - Names and Identifiers
5H-dibenz[b,f]azepine-5-carbonitrile - Physico-chemical Properties
| Molecular Formula | C15H10N2 |
| Molar Mass | 218.25 |
| Melting Point | 106-110°C(lit.) |
5H-dibenz[b,f]azepine-5-carbonitrile - Risk and Safety
| WGK Germany | 3 |
5H-dibenz[b,f]azepine-5-carbonitrile - Introduction
5-Cyano-5H-dibenz [B, f]azepine(5-Cyano-5H-dibenz [B, f]azepine) is an organic compound. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
-Appearance: 5-Cyano-5H-dibenz [B, f]azepine is a white to light yellow crystalline solid.
-Molecular formula: C16H11N3
-Molecular Weight: 257.28
-Melting point: about 135-138 ° C.
-Solubility: Soluble in general organic solvents.
Use:
- 5-Cyano-5H-dibenz [B, f]azepine is widely used in the field of medicine to synthesize drugs.
-As a drug intermediate, it can be used to synthesize antidepressants and antipsychotic drugs, such as thiabepramine (Sertraline) and serotinamide (Ziprasidone).
Method:
The preparation method of 5-Cyano-5H-dibenz [B, f]azepine is more complicated, usually involving multi-step reactions. A common preparation method is to obtain the target product by multiple reactions and purification starting from difluorophenyl hydrophobic amine (Fluorobenzylamine) and benzoic acid (Phenylacetic acid).
Safety Information:
- 5-Cyano-5H-dibenz [B, f]azepine is less toxic. However, as an organic compound, it should follow general safety practices.
-Avoid skin contact, inhalation or ingestion during operation. Wear protective gloves and a mask to ensure that the operation is carried out in a well-ventilated laboratory environment.
-In the event of accidental exposure or ingestion, seek medical attention immediately and inform the physician that 5-Cyano-5H-dibenz [B, f]azepine is used.
Nature:
-Appearance: 5-Cyano-5H-dibenz [B, f]azepine is a white to light yellow crystalline solid.
-Molecular formula: C16H11N3
-Molecular Weight: 257.28
-Melting point: about 135-138 ° C.
-Solubility: Soluble in general organic solvents.
Use:
- 5-Cyano-5H-dibenz [B, f]azepine is widely used in the field of medicine to synthesize drugs.
-As a drug intermediate, it can be used to synthesize antidepressants and antipsychotic drugs, such as thiabepramine (Sertraline) and serotinamide (Ziprasidone).
Method:
The preparation method of 5-Cyano-5H-dibenz [B, f]azepine is more complicated, usually involving multi-step reactions. A common preparation method is to obtain the target product by multiple reactions and purification starting from difluorophenyl hydrophobic amine (Fluorobenzylamine) and benzoic acid (Phenylacetic acid).
Safety Information:
- 5-Cyano-5H-dibenz [B, f]azepine is less toxic. However, as an organic compound, it should follow general safety practices.
-Avoid skin contact, inhalation or ingestion during operation. Wear protective gloves and a mask to ensure that the operation is carried out in a well-ventilated laboratory environment.
-In the event of accidental exposure or ingestion, seek medical attention immediately and inform the physician that 5-Cyano-5H-dibenz [B, f]azepine is used.
Last Update：2024-04-09 02:00:51
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